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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RANGAP1 All Species: 13.33
Human Site: T485 Identified Species: 22.56
UniProt: P46060 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46060 NP_002874.1 587 63542 T485 S V F K D E A T V R M A V Q D
Chimpanzee Pan troglodytes XP_001169198 587 63551 T485 S V F K D E A T V R T A V Q D
Rhesus Macaque Macaca mulatta XP_001099367 1074 115836 A539 S V F K D E A A V R T A V Q D
Dog Lupus familis XP_538355 1323 142434 P485 S V F K D E A P V R T A V Q D
Cat Felis silvestris
Mouse Mus musculus P46061 589 63598 S487 S V F R D D A S V K T A V L D
Rat Rattus norvegicus NP_001012199 431 46388 G334 D L N G N A L G E E G C E Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509116 589 63641 S487 S V L K D D V S V K T A V Q E
Chicken Gallus gallus NP_001006237 580 63057 Q478 S V F K D E A Q V K T A V H E
Frog Xenopus laevis O13066 580 62889 E478 S V Y R E D G E I K A A V E E
Zebra Danio Brachydanio rerio NP_001070084 570 61996 A463 S V Y K D N D A E V K S A V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VIW3 596 66051 Q488 A L Q S I V N Q F T G D N H L
Honey Bee Apis mellifera XP_395378 580 63771 S462 K V S A L S T S G Y V D V R L
Nematode Worm Caenorhab. elegans P34342 960 105635 R644 T V E W F D V R Q N G I H E E
Sea Urchin Strong. purpuratus XP_001185909 387 41323 V290 A N S L R E G V P S L K E L N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 52.7 41.4 N.A. 88.6 66.6 N.A. 83.6 81.7 67.9 60.8 N.A. 32.3 43.6 25 40.7
Protein Similarity: 100 99.1 53.7 43 N.A. 95.5 70.6 N.A. 91.5 91.6 83.8 78 N.A. 53.1 59.9 38.2 54.8
P-Site Identity: 100 93.3 86.6 86.6 N.A. 60 6.6 N.A. 53.3 66.6 26.6 26.6 N.A. 0 13.3 6.6 6.6
P-Site Similarity: 100 93.3 86.6 86.6 N.A. 86.6 20 N.A. 80 80 80 40 N.A. 13.3 33.3 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 8 0 8 43 15 0 0 8 58 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 8 0 0 0 58 29 8 0 0 0 0 15 0 0 36 % D
% Glu: 0 0 8 0 8 43 0 8 15 8 0 0 15 15 29 % E
% Phe: 0 0 43 0 8 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 15 8 8 0 22 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 15 0 % H
% Ile: 0 0 0 0 8 0 0 0 8 0 0 8 0 0 0 % I
% Lys: 8 0 0 50 0 0 0 0 0 29 8 8 0 0 0 % K
% Leu: 0 15 8 8 8 0 8 0 0 0 8 0 0 15 29 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 8 8 0 8 8 8 0 0 8 0 0 8 0 8 % N
% Pro: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 15 8 0 0 0 0 43 0 % Q
% Arg: 0 0 0 15 8 0 0 8 0 29 0 0 0 8 0 % R
% Ser: 65 0 15 8 0 8 0 22 0 8 0 8 0 0 0 % S
% Thr: 8 0 0 0 0 0 8 15 0 8 43 0 0 0 0 % T
% Val: 0 79 0 0 0 8 15 8 50 8 8 0 65 8 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 15 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _